Principal Bioinformatics Scientist
Baylor GeneticsUnited States
Posted October 23, 2025
Full Time
About the Company
Baylor Genetics is a leading diagnostic genomics partner that delivers a comprehensive suite of clinically relevant genetic tests, including Whole Genome Sequencing, Whole Exome Sequencing, and specialized panels. The company’s core focus spans family planning, pregnancy, neonatal and pediatric care, oncology, and rare disease diagnostics, providing rapid, precision results that help clinicians avoid lengthy diagnostic journeys. Distinctive to the industry, Baylor Genetics integrates dedicated genetic counselors into every testing process, ensuring personalized guidance for patients and healthcare providers alike. Operating from Houston’s Texas Medical Center, the lab serves clients nationwide, combining cutting‑edge technology with a patient‑centric culture that attracts top talent in clinical genetics and laboratory science.
Job Description
Baylor Genetics is seeking an accomplished Principal Bioinformatics Scientist to join the Bioinformatics R&D and Data Science organization.
Requirements
- Master's or higher degree (PhD preferred) in Bioinformatics, Computational Biology, Genomics, Computer Science, or a related quantitative field.
- 6+ years of professional experience in bioinformatics, computational genomics, or computational biology, including extensive hands-on work with large-scale NGS datasets.
- Strong experience with NGS data formats and tools, including Nextflow, Snakemake, and Cromwell.
- Proficiency in Python and R, with familiarity with one or more compiled languages (C/C++, Java, or similar).
- Experience working in a clinical genomics or regulated diagnostic environment.
- Strong scientific reasoning and analytical problem-solving abilities.
- Hands-on approach to both R&D innovation and operational troubleshooting.
- Ability to collaborate effectively with multidisciplinary teams.
- Excellent written and verbal communication skills.
- Commitment to quality, compliance, and scientific excellence in a clinical setting.
Benefits
- Paid Time Off
- 401k Matching
- Retirement Plan