VP, CMC & Technical Operations
Character BioSan Francisco, California, United States
Posted September 16, 2025
Full Time
About the Company
Character Bio is a precision medicine company focused on transforming drug development for progressive, polygenic diseases, particularly in ophthalmology. By integrating genetics with clinical and imaging data from over 150 clinics, the company reclassifies complex diseases into genetically defined subtypes to identify novel therapeutic targets. Their AI-powered platform combines genomics, multi-modal data, and machine learning to develop more precise therapies, with lead programs advancing toward clinical trials for treating age-related blindness.
Job Description
Character Biosciences is seeking a VP of CMC & Technical Operations to lead all Chemistry, Manufacturing, and Controls (CMC) activities, focusing on early development and clinical supply. This role will drive process and analytical development, regulatory CMC strategy, and CDMO oversight to support IND/IMPD filings and ensure reliable supply for Phase 1-3 clinical trials. The company is pioneering targeted therapies for polygenic diseases and has experience in ophthalmology.
Requirements
- Advanced degree in chemistry, biochemistry, engineering, or related field.
- 12+ years of biopharma experience.
- Expertise in process development, manufacturing, and regulatory CMC.
- Proven track record of supporting IND/IMPD submissions and early clinical trial supply.
- Hands-on experience with CDMO management and GMP manufacturing.
