Postdoc / Visiting Scientist – Bioengineering CV Research models

Kardigan is seeking a postdoc / visiting scientist with a bioengineering background to help build physiologically relevant in vitro models to study cardiovascular diseases. The project aims to model cardiovascular health and disease into engineered heart tissue models, enabling high-throughput multi-well mechanistic and physiological assessments in vitro.

Requirements

• Design, fabricate, and optimize 3D EHT constructs using atrial, ventricular myocardium, and aortic valve leaflets.
• Integrate various cell types into tissue constructs and in vitro models.
• Perform in vitro functional measurements of contractility as well as tissue compliance/stiffness.
• Analyze differences between healthy vs. disease models to understand pathophysiology and disease mechanism.
• Conduct immunohistochemistry, confocal microscopy, qPCR, and Western blotting to evaluate structural and functional markers.
• Conduct in vitro assay screening of Kardigan compounds.
• Perform quantitative analysis of biomechanical and molecular data, create reports and communicate findings to company-wide meetings.

Benefits

• 401k Matching
• Retirement Plan
• Generous Paid Time Off
• Tuition Reimbursement
• Visa Sponsorship
• Four Day Work Week
• Generous Parental Leave
• Relocation Assistance