Scientist/Sr. Scientist, Antibody Characterization
Manifold BioBoston, Massachusetts, United States
Posted October 22, 2025
Full Time
About the Company
Manifold Bio is a pioneering tissue-specific medicines company focused on developing targeted biologics using a high-throughput in vivo discovery engine. This innovative approach combines massively multiplexed in vivo screening with AI-powered design to optimize pharmacokinetics and biodistribution, solving previously intractable challenges for tissue-specific delivery. By generating rich datasets, Manifold Bio accelerates the development of effective therapeutics, paving the way for faster patient access.
Job Description
Manifold Bio is seeking a skilled Scientist/Sr. Scientist to join their Protein Sciences team and help expand the frontiers of shuttle-enabled drug delivery. The role involves driving innovative projects to assess protein-protein interactions and molecule characteristics using high-throughput methods. This position will inform future therapeutic programs and contribute to expanding Manifold's platform. The team utilizes a proprietary protein barcoding technology and a novel in vivo-centric discovery approach.
Requirements
- PhD or equivalent experience in protein biochemistry, molecular biology, biological engineering, or related field
- Proven expertise in protein analytics and protein-protein interactions utilizing techniques such as BLI, SPR, ELISA, aSEC, DLS, and CE-SDS/cIEF
- Proficiency in protein expression and characterization laboratory techniques
- Strong analytical skills and creative problem-solving abilities
- Adaptable and proactive mindset
- Strong communication skills
- Collaborative working style
