Principal Scientist, Process Chemistry

We're seeking a Principal Scientist in Process Chemistry to lead drug substance activities for one or more projects within Praxis' portfolio to support clinical and commercial supply.

Requirements

• Lead Process Chemistry Research and Development for one or more projects from early to late phase within Praxis.
• Design early phase and late-phase/commercial drug substance process and lead their demonstration from lab to pilot plant.
• Provide chemistry and technical leadership throughout the lifecycle of the drug substance.
• Identify final API forms for pharmaceutical development.
• Collaborate and lead external CRO and CDMO organizations to achieve deliverables.
• Author or co-author regulatory submissions.
• Define manufacturing strategy and execution, including GMP requirements and issue resolution.
• Manage quarterly budgeting of drug substance relevant activities.

Benefits

• 99% of the premium paid for medical, dental, and vision plans
• Company-paid life insurance
• AD&D, disability benefits
• Voluntary plans to personalize coverage
• Dollar-for-dollar matching up to 6% on eligible 401(k) contributions
• Long-term stock incentives and ESPP
• Discretionary quarterly bonus
• Flexible wellness benefit
• Generous PTO
• Paid holidays and company-wide shutdowns