Executive Medical Director, Clinical Development
Spyre TherapeuticsNew London, Connecticut, United States
Posted October 28, 2025
365000 - 396000 USD year
Full Time
About the Company
Spyre Therapeutics is a clinical-stage biotechnology company specializing in the development of next-generation treatments for inflammatory bowel disease (IBD) and other immune-mediated disorders. The company leverages advanced antibody engineering, dose optimization, and strategic therapeutic combinations to create extended half-life antibodies targeting α4β7, TL1A, and IL-23, offering a distinctive approach to address unmet medical needs in the field.
Job Description
Spyre Therapeutics is a clinical-stage biotech company focused on developing next-generation inflammatory bowel disease (IBD) therapies. They are seeking an Executive Medical Director of Clinical Development to lead the execution of clinical programs evaluating innovative antibody therapeutics. This role involves designing, planning, and overseeing clinical trials, collaborating across functions, and ensuring regulatory compliance.
Requirements
- MD or equivalent medical degree
- Board certification in relevant specialty (preferred)
- 6+ years clinical development experience
- Significant experience in immunology and/or inflammation
- Experience with antibody therapeutics
- Demonstrated success in designing and executing IBD trials
- Deep understanding of GCP, clinical trial design, biostatistics, and global regulatory expectations
Benefits
- Market competitive compensation
- Performance bonus
- Equity grant opportunities
- Health, welfare & retirement benefits
- Remote working environment
