Senior Statistical Data Scientist

Praxis is seeking a Senior Statistical Data Scientist to support the development, validation and automation of analytical pipelines and statistical models that support metadata-driven clinical data processing, reporting, and regulatory submissions.

Requirements

• Support the design, development, and validation of R/Python code to automate generation of analytical datasets and TLFs within a metadata-driven pipeline.
• Translate SAPs and metadata specifications (YAML/CSV) into executable and reproducible code.
• Build and validate R packages and data science tools supporting both exploratory and confirmatory analyses, ensuring full traceability and audit readiness.
• Implement and validate statistical models (e.g., MMRM, ANCOVA, logistic regression) using R packages such as mmrm, emmeans.
• Collaborate with IT to integrate data science and statistical programming workflows within Databricks and CI/CD pipelines for continuous validation and reproducibility
• Collaborate across programming, biostatistics, and data standards functions to ensure dataset definitions, derivations, and metadata align with controlled standards.
• Conduct peer code reviews, unit testing, and automated validation; ensuring deliverables meet submission-quality and reproducibility standards
• Mentor and guide team members in best practices for programming, validation, and automation

Benefits

• 99% of the premium paid for medical, dental and vision plans
• Company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage
• Dollar-for-dollar matching on eligible 401(k) contributions up to 6%
• Long-term stock incentives and ESPP
• Discretionary quarterly bonus
• Extremely flexible wellness benefit
• Generous PTO, paid holidays and company-wide shutdowns